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How Scientists Are Stopping COVID-19: The Hunt for 3CLpro Inhibitors!

Discover how scientists are combating COVID-19 by targeting its core engine—the 3CLpro protein. In this video, we break down the crucial role of the 3CLpro protease in the virus’s life cycle and explore cutting-edge research methods like molecular docking and dynamics simulations. See how researchers use these tools to identify potential inhibitors that could block the virus from replicating. Learn about the rigorous process of testing these candidates and selecting the most promising ones for real-world clinical trials. If you found this deep dive into COVID-19 drug discovery fascinating, don’t forget to like and share the video with anyone interested in science and medical breakthroughs!

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Phosphorus-rich Grains In Ryugu Samples With Major Biochemical Potential

Parent bodies of C-type asteroids may have brought key volatile and organic-rich compounds to the terrestrial planets in the early stages of the Solar System . At the end of 2020, the JAXA Hayabusa2 mission successfully returned samples from Ryugu, providing access to a primitive matter that has not suffered terrestrial alteration. Here we report the discovery of a peculiar class of grains, up to a few hundreds of micrometres in size, that have a hydrated ammonium–magnesium–phosphorus (HAMP)-rich composition. Their specific chemical and physical properties point towards an origin in the outer Solar System , beyond most snow lines, and their preservation along Ryugu history. These phosphorus-rich grains, embedded within an organic-rich phyllosilicate matrix, may have played a major role when immersed in primitive terrestrial water reservoirs. In particular, in contrast to poorly soluble calcium-rich phosphates, HAMP grains favour the release of phosphorus-rich and nitrogen-rich ionic s...
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